They are distinguished by an additional X chromosome. A defect in the genes of both calico and Tortoiseshell cats causes sterility to occur in one in every three thousand of these cats. When you look at a tortoiseshell cat, you'll notice that her coat has almost no white markings. While the genetics of both types of cats are identical, calico cats have one extra copy of the allele responsible for white spots. Cats can be either calico or tortoiseshell, but not both. The attitude or nature of the Tortie cat is fierce, independent, possessive towards its owner, strong-willed, unpredictable, hot-tempered, etc., whereas the attitude or nature of the Calico cat is very fierce, highly tempered, strong-willed, and very aggressive some of the behavior is – hissing, swatting, and biting.Calico and tortoiseshell are the names used to describe the pattern and coloring of a cat's hair.
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